Patient characteristics at entry to the study
| Characteristic | Ropinirole (n = 146) | Placebo (n = 138) |
|---|---|---|
| Values are mean (SD) unless stated otherwise. | ||
| *One patient had a baseline IRLS total score of 14 despite an entry criterion of ⩾15. | ||
| †Patients with a score of ⩾4 on the CGI “severity of illness” scale are considered to be moderately ill or worse. | ||
| CGI, clinical global impression; IRLS, international restless legs scale. | ||
| Age (years) | 54.0 (11.1) | 56.2 (11.2) |
| Range (years) | 30 to 78 | 28 to 77 |
| Women (n (%)) | 88 (60.3) | 91 (65.9) |
| Age at onset of symptoms (years) | 37.6 (17.1) | 38.9 (16.4) |
| Range (years) | 5 to 73 | 4 to 72 |
| Duration of symptoms (years) | 16.4 (14.1) | 17.3 (14.9) |
| Range (years) | <1 to 60 | <1 to 61 |
| Time of day when symptoms are mainly present (n (%)): | ||
| Night-time only | 22 (15.1) | 18 (13.0) |
| Evening and night-time | 109 (74.7) | 108 (78.3) |
| Daytime, evening and night-time | 15 (10.3) | 12 (8.7) |
| IRLS total score at baseline | 24.4 (5.75) | 25.2 (5.63) |
| Range | 14* to 40 | 15 to 40 |
| CGI “severity of illness” score of ⩾4† (n (%)) | 126 (86.3) | 123 (89.1) |