Table 5

Comparison of change scores of motor and cognitive functions in clozapine and placebo groups

ScoresPeriod IIPeriod III
Clozapine (N = 32)Placebo (N = 28)p ValueAll patients (N = 54)
MMSE, mini mental test examination; UPDRS, unified Parkinson’s disease rating scale.
MMSE0.0 (1.8)−0.3 (3.1)0.60−0.2 (3.3)
Total UPDRS−3.5 (9.1)−4.2 (9.6)0.81−5.1 (8.3)
Motor UPDRS−3.5 (7.7)−3.0 (8.1)0.85−3.4 (6.4)