Mean (SD) severity score for ML, CAA, and Art in each of the four brain regions investigated according to possession of 0, 1, or 2 APO E e4 alleles
| e4 alleles | Number of cases | Frontal | Temporal | Parietal | Occipital | |
|---|---|---|---|---|---|---|
| *p<0.05 and **p<0.01 compared to occipital cortex. | ||||||
| ML | None | 21 | 0.9 (1.0) | 0.7 (0.9) | 0.8 (0.9) | 1.0 (0.7) |
| 1 | 30 | 0.3 (0.7)** | 0.4 (0.7)** | 1.1 (1.0) | 1.2 (0.9) | |
| 2 | 10 | 0.3 (0.7)** | 0.6 (1.1)* | 0.6 (0.7)* | 1.4 (0.8) | |
| CAA | None | 36 | 1.5 (0.8)** | 1.6 (0.7)* | 1.7 (0.9) | 2.5 (0.8) |
| 1 | 43 | 1.7 (0.8) | 1.6 (0.8) | 1.7 (0.9) | 2.0 (0.9) | |
| 2 | 15 | 1.9 (0.8)* | 1.8 (0.6)** | 1.9 (1.1) | 2.5 (0.8) | |
| Art | None | 31 | 2.6 (2.2) | 2.2 (2.5) | 2.9 (2.6) | 3.3 (2.3) |
| 1 | 39 | 1.9 (2.2)** | 2.3 (1.8) | 3.0 (2.4) | 3.2 (2.6) | |
| 2 | 41 | 2.8 (2.6) | 1.9 (2.2)* | 2.7 (2.7) | 4.5 (2.5) | |