Association of distress proneness with baseline level of function and annual rate of change in different cognitive domains, based on separate random effects models*
| Cognitive domain | Model term | Estimate | SE | p Value |
|---|---|---|---|---|
| *Results show the effect of a 1 unit change in the distress proneness score. Age, sex, and education and their interactions with time (measured in years) were also adjusted for in each model. | ||||
| Episodic memory | Distress proneness | −0.019 | 0.008 | 0.021 |
| Time | −0.275 | 0.032 | <0.001 | |
| Distress proneness × time | −0.001 | 0.003 | 0.795 | |
| Visuoconstruction | Distress proneness | −0.011 | 0.010 | 0.264 |
| Time | −0.524 | 0.071 | <0.001 | |
| Distress proneness × time | −0.011 | 0.008 | 0.128 | |
| Repetition | Distress proneness | −0.012 | 0.010 | 0.240 |
| Time | −0.615 | 0.068 | <0.001 | |
| Distress proneness × time | 0.004 | 0.007 | 0.541 | |
| Naming | Distress proneness | 0.003 | 0.011 | 0.793 |
| Time | −0.768 | 0.084 | <0.001 | |
| Distress proneness × time | −0.005 | 0.009 | 0.552 | |
| Global cognition | Distress proneness | −0.010 | 0.008 | 0.172 |
| Time | −0.547 | 0.054 | <0.001 | |
| Distress proneness × time | <0.001 | 0.006 | 0.983 | |