Table 2

Comparison of controls and patients of varying CDR grading

VariablesControlsCDR = 0CDR = 0.5CDR⩾1
Values are mean (SD) or number (%).
*Values are median (interquartile range); †differs significantly from controls, p<0.05; ‡differs significantly from CDR = 0, p<0.05; §differs significantly from CDR = 0.5, p<0.05; ¶differs significantly from CDR⩾1, p<0.05.
NA, not applicable, F, female.
n4239 (52%)26 (34.7%)10 (13.3%)
Age69.6 (9.9)69.4 (12.8)70.2 (8.8)77.1 (8.7)
Gender, n (% F)24 (58.5%)20 (51.3%)12 (46.2%)4 (40.0%)
Years of education5.4 (4.6)4.1 (3.7)5.8 (4.4)5.5 (4.8)
NIHSSNA4.1 (2.7)5.8 (4.4)5.5 (4.8)
HTNA32 (82.1%)23 (88.5%)9 (90.9%)
DMNA18 (46.2%)6 (23.1%)4 (40.0%)
Previous strokeNA8 (21.6%)4 (15.4%)5 (50.0%)
HyperlipidaemiaNA11 (28.2%)9 (34.6%)3 (30.0%)
Heart diseasesNA5 (12.8%)4 (15.4%)1 (10.0%)
History of smokingNA13 (33.3%)13 (50.0%)3 (30.0%)
History of drinkingNA11 (28.2%)9 (34.6%)1 (10.0%)
BI20.0 (0.0)¶18.5 (3.4)18.5 (3.8)16.6 (3.0)†
IADL0.1 (0.2)‡§¶0.7 (0.7)†¶0.8 (0.7)†¶1.6 (1.0)†‡§
Sites of recent infarcts
    StriatocapsuleNA9 (23.1%)4 (15.4%)2 (20.0%)
    Cerebral white matterNA5 (12.8%)8 (30.8%)4 (40.0%)
    ThalamusNA10 (25.6%)7 (26.9%)1 (10.0%)
    CerebellumNA0 (0.0%)1 (3.8%)0 (0.0%)
    BrainstemNA15 (38.5%)6 (23.1%)3 (30.0%)
No. of silent infarcts*NA0.5 (2.0)0.0 (2.0)2.0 (2.3)
WMC*NA5.5 (8.5)4.0 (3.0)13.0 (14.8)
Pre-stroke IQCODENA3.1 (0.2)§¶3.3 (0.3)‡¶3.7 (0.4)‡§
MMSE27.7 (2.1)§¶26.2 (3.4)¶24.9 (3.8)†¶19.6 (6.3)†‡§
MDRS I/P34.1 (3.0)‡§¶30.0 (5.2)†¶29.0 (5.4)†¶21.3 (8.3)†‡§
ADAS-cog9.5 (3.4)‡§¶14.4 (6.9)†¶16.0 (6.7)†¶26.9 (16.6)†‡§