Comparison of controls and patients of varying CDR grading
| Variables | Controls | CDR = 0 | CDR = 0.5 | CDR⩾1 |
|---|---|---|---|---|
| Values are mean (SD) or number (%). | ||||
| *Values are median (interquartile range); †differs significantly from controls, p<0.05; ‡differs significantly from CDR = 0, p<0.05; §differs significantly from CDR = 0.5, p<0.05; ¶differs significantly from CDR⩾1, p<0.05. | ||||
| NA, not applicable, F, female. | ||||
| n | 42 | 39 (52%) | 26 (34.7%) | 10 (13.3%) |
| Age | 69.6 (9.9) | 69.4 (12.8) | 70.2 (8.8) | 77.1 (8.7) |
| Gender, n (% F) | 24 (58.5%) | 20 (51.3%) | 12 (46.2%) | 4 (40.0%) |
| Years of education | 5.4 (4.6) | 4.1 (3.7) | 5.8 (4.4) | 5.5 (4.8) |
| NIHSS | NA | 4.1 (2.7) | 5.8 (4.4) | 5.5 (4.8) |
| HT | NA | 32 (82.1%) | 23 (88.5%) | 9 (90.9%) |
| DM | NA | 18 (46.2%) | 6 (23.1%) | 4 (40.0%) |
| Previous stroke | NA | 8 (21.6%) | 4 (15.4%) | 5 (50.0%) |
| Hyperlipidaemia | NA | 11 (28.2%) | 9 (34.6%) | 3 (30.0%) |
| Heart diseases | NA | 5 (12.8%) | 4 (15.4%) | 1 (10.0%) |
| History of smoking | NA | 13 (33.3%) | 13 (50.0%) | 3 (30.0%) |
| History of drinking | NA | 11 (28.2%) | 9 (34.6%) | 1 (10.0%) |
| BI | 20.0 (0.0)¶ | 18.5 (3.4) | 18.5 (3.8) | 16.6 (3.0)† |
| IADL | 0.1 (0.2)‡§¶ | 0.7 (0.7)†¶ | 0.8 (0.7)†¶ | 1.6 (1.0)†‡§ |
| Sites of recent infarcts | ||||
| Striatocapsule | NA | 9 (23.1%) | 4 (15.4%) | 2 (20.0%) |
| Cerebral white matter | NA | 5 (12.8%) | 8 (30.8%) | 4 (40.0%) |
| Thalamus | NA | 10 (25.6%) | 7 (26.9%) | 1 (10.0%) |
| Cerebellum | NA | 0 (0.0%) | 1 (3.8%) | 0 (0.0%) |
| Brainstem | NA | 15 (38.5%) | 6 (23.1%) | 3 (30.0%) |
| No. of silent infarcts* | NA | 0.5 (2.0) | 0.0 (2.0) | 2.0 (2.3) |
| WMC* | NA | 5.5 (8.5) | 4.0 (3.0) | 13.0 (14.8) |
| Pre-stroke IQCODE | NA | 3.1 (0.2)§¶ | 3.3 (0.3)‡¶ | 3.7 (0.4)‡§ |
| MMSE | 27.7 (2.1)§¶ | 26.2 (3.4)¶ | 24.9 (3.8)†¶ | 19.6 (6.3)†‡§ |
| MDRS I/P | 34.1 (3.0)‡§¶ | 30.0 (5.2)†¶ | 29.0 (5.4)†¶ | 21.3 (8.3)†‡§ |
| ADAS-cog | 9.5 (3.4)‡§¶ | 14.4 (6.9)†¶ | 16.0 (6.7)†¶ | 26.9 (16.6)†‡§ |