Table 1

Baseline demographics and disease characteristics

TotalPlaceboIFN
*p<0.05.
EDSS, Expanded Disability Status Scale; IFN, interferon (Rebif® 22 μg once weekly); MS, multiple sclerosis; RFSS, Regional Functional Status Scale; SPMS, secondary progressive multiple sclerosis.
Number of patients364178186
Proportion female0.600.600.60
Age (mean, years)45.746.445.1
Duration of MS (mean, years)14.314.414.2
Duration of SPMS (mean, years)*5.46.14.8
Number of relapses in prior 4 years (mean)1.71.61.7
Proportion relapse free in prior 4 years0.370.400.34
EDSS score (mean)*4.85.04.7
RFSS score (mean)16.516.816.2
Arm index (mean)1.41.41.4
Ambulation index* (mean)3.33.53.1