Review of published reports on recanalisation and outcome of patients with basilar artery occlusion treated with thrombolysis
Source | No of patients (mode of treatment) | Maximum time window | Partial or complete recanalisation (n (%)) | Favourable outcome (n (%)), measured by: | Survival (n (%)) |
---|---|---|---|---|---|
Barthel, Barthel index of activities of daily living; ia, intra-arterial; iv, intravenous; MRS, modified Rankin scale score. | |||||
Hacke3 | 43 (ia) | >72 hours | 19 (44%) | 10 (23%) (no, minimal, or moderate deficit) | 14(33%) |
Zeumer4 | 28 (ia) | Not indicated (mean 8 hours) | 21 (75%) | 10 (35%) (able to work) | 18(64%) |
Becker14 | 12 (ia) | 48 hours | 9 (75%) | 3 (25%) (minimal deficits) | 3(25%) |
Brandt5 | 42 (ia)/9 (iv) | 48 hours | 26 (51%) | 10 (20%) (Barthel ⩾95) | 16(31%) |
Cross15 | 24 (ia) | 82 hours | Not indicated | 6 (25%) (mRS ⩽2) | 9(38%) |
Huemer16 | 16 (iv) | 7 hours | 10 (62%) | 3 (19%) (independence from constant support) | 5(31%) |
Present study | 40 (ia) | 12 hours | 32 (80%) | 14 (35%) (mRS ⩽2) | 23(58%) |