Characteristics of Alzheimer cases and family controls without dementia*
| Alzheimer cases (n = 426) | Controls without dementia (n = 545) | Probability† | |
|---|---|---|---|
| *Values are given as mean (standard deviation, SD) or as number (percent, adjusted for age tertile). | |||
| †Probability values are from a generalised estimating equations model that accounts for familial correlation and adjusts for age. | |||
| ApoE, apolipoprotein E genotype; n, number; NSAID, non-steroidal anti-inflammatory drug. | |||
| Age, years | 71.1 (SD 8.1) | 65.0 (SD 8.6) | <0.0001 |
| Education, 12 years or more | 218 (53%) | 384 (69%) | <0.0001 |
| Ethnicity, African American | 162 (35%) | 125 (23%) | <0.0001 |
| Oestrogen use for more than 6 months | 87 (21%) | 192 (35%) | 0.0007 |
| ApoE, at least oneε4 allele | 281 (66%) | 201 (37%) | <0.0001 |
| Alcohol, more than 0.25 drinks/day | 106 (25%) | 163 (27%) | 0.7 |
| Smoking history,current or past | 149 (37%) | 196 (35%) | 0.3 |
| NSAID use for more than 6 months | 20 (5%) | 86 (16%) | <0.0001 |
| History of hysterectomy or oophorectomy | 141 (35%) | 231 (42%) | 0.016 |