Table 2

 Age stratified risk of Alzheimer’s disease associated with prior use of hormone therapy

Number of Alzheimer casesNumber of controls without dementiaCrude OR(95% CI)Adjusted OR(95% CI)*
*Adjusted for age, education, and ethnicity.
CI, confidence interval; HT, oestrogen containing hormone therapy.
Entire sample (ages 50–99)
    No HT339353ReferenceReference
    HT871920.47 (0.35 to 0.63)0.70 (0.51 to 0.95)
First age tertile (50–63 years)
    No HT58135ReferenceReference
    HT171120.35 (0.19 to 0.64)0.35 (0.19 to 0.66)
Second age tertile (64–71 years)
    No HT105127ReferenceReference
    HT28520.65 (0.39 to 1.1)0.86 (0.50 to 1.5)
Third age tertile (72–99 years)
    No HT17691ReferenceReference
    HT42280.78 (0.47 to 1.3)0.97 (0.57 to 1.6)