Table 1

Atrophic regions in patients with early onset Alzheimer’s disease compared with the younger controls and in patients with late onset Alzheimer’s disease compared with the older controls (p<0.05 corrected for multiple comparisons)

Cluster size k	Region	Stereotactic coordinates (mm)			z score
Cluster size k	Region	x	y	z	z score
L, left; R, right.
EOAD patients v younger controls
1180	R superior temporal gyrus	60	−30	16	5.91
	R supramarginal gyrus	60	−48	20	5.38
	R middle temporal gyrus	62	−44	−6	4.86
1740	L precuneus	−30	−68	42	5.58
	L superior parietal lobule	−22	−64	56	5.23
	L superior parietal lobule	−32	−56	50	5.23
307	R middle frontal gyrus	28	2	60	5.13
	R middle frontal gyrus	28	16	60	5.13
502	L postcentral gyrus	−58	−30	20	5.10
	L superior temporal gyrus	−60	−50	14	4.68
94	L hippocampus (head)	−34	−20	−20	4.67
20	L inferior frontal gyrus	−44	32	6	4.60
4	R fusiform gyrus	52	−42	−22	4.33
LOAD patients v older controls
1168	L hippocampus (head)	−32	−16	−22	5.87
522	R hippocampus (head)	30	−8	−20	5.67
	R hippocampus (body)	32	−30	−6	4.40
177	R inferior temporal gyrus	46	−4	−44	5.19
	R inferior temporal gyrus	46	−14	−38	4.85
	R inferior temporal gyrus	52	−20	−34	4.77
110	R superior temporal gyrus	40	22	−34	4.95
15	L superior temporal gyrus	−24	12	−46	4.74
6	R inferior temporal gyrus	66	−18	−20	4.39
5	L inferior temporal gyrus	−52	−14	−32	4.38