HAART related drug toxicities
| Drug | Toxicity |
|---|---|
| Nucleoside reverse transcriptase inhibitors (NRTIs) | |
| Class associated | Lactic acidosis, hepatic steatosis, lipodystrophy |
| Drug specific | |
| Zidovudine | Myelosuppression, myopathy |
| Stavudine (d4T) | Peripheral neuropathy |
| Zalcitabine (ddC) | Peripheral neuropathy |
| Didanosine (ddI) | Peripheral neuropathy, pancreatitis |
| Lamivudine (3TC) | ? Neuropathy |
| Non-NRTIs | |
| Efavirenz | Dysphoria, mood changes, vivid dreams, hypercholesterolaemia |
| Nevirapine | Hepatitis, Stevens-Johnson syndrome |
| Protease inhibitors | |
| Class associated | Lipodystrophy, hyperlipidaemia, diabetes |
| Drug specific | |
| Nefinavir | Diarrhoea |
| Indinivir | Nephrolithiasis |
| Ritonivir | Perioral dysaesthesia, flushing, diarrhoea, hyperuricaemia |
| Amprenivir | Diarrhoea |
| Lopinivir | Diarrhoea |