Table 5

 Clinical and biological clues that indicated an elevated risk of cancer in patients with classical syndromes and no onconeural antibodies

Limbic encephalitisNegative VGKC antibodies and no recovery with immunotherapy
Subacute cerebellar degenerationPositive VGCC antibodies or association with LEMS
Opsoclonus-myoclonus syndromeAge <5 or >40 years or no recovery with immunotherapy
Sensory neuronopathyAge >40 years and smoking habit
LEMSAge >40 years and smoking habit
DermatomyositisAge >40 years