Clinical and biological clues that indicated an elevated risk of cancer in patients with classical syndromes and no onconeural antibodies
| Syndrome | Clues |
|---|---|
| Limbic encephalitis | Negative VGKC antibodies and no recovery with immunotherapy |
| Subacute cerebellar degeneration | Positive VGCC antibodies or association with LEMS |
| Opsoclonus-myoclonus syndrome | Age <5 or >40 years or no recovery with immunotherapy |
| Sensory neuronopathy | Age >40 years and smoking habit |
| LEMS | Age >40 years and smoking habit |
| Dermatomyositis | Age >40 years |