The main outcome measures in the three patient groups
| FSHD (n = 139) | MD (n = 322) | HMSN-I (n = 137) | p Value | |
|---|---|---|---|---|
| Values are mean (SD). A higher value indicates more complaints or impairments. | ||||
| *Significantly different from FSHD, Bonferroni p<0.05. | ||||
| †Significantly different from MD, Bonferroni p<0.05. | ||||
| ‡Significantly different from HMSN-I, Bonferroni p<0.05. | ||||
| FSHD, facioscapulohumeral muscular dystrophy; HMSN-I, hereditary motor and sensory neuropathy type I; MD, adult onset myotonic dystrophy; SF-36, 36 item short form general health questionnaire. | ||||
| CIS | ||||
| CIS-fatigue | 36.5 (12.5)† | 40.4 (11.8)*‡ | 37.4 (12.2)† | 0.002 |
| CIS-concentration | 12.3 (8.2)† | 16.8 (8.3)*‡ | 13.8 (8.7)† | 0.000 |
| CIS-motivation | 12 (5.9)† | 16.8 (6.6)*‡ | 12.2 (6.1)† | 0.000 |
| CIS-activity | 10.1 (5.5)† | 13.2 (5.6)*‡ | 9.4 (5.5)† | 0.000 |
| SF-36 | ||||
| physical functioning | 45.2 (31.4) | 48.4 (28.2) | 53.1 (26.4) | NS |
| social functioning | 71.6 (24.2) | 69.9 (24.3) | 67.5 (24.3) | NS |
| role limitations physical | 47.9 (42) | 48.2 (39.7) | 48.9 (39) | NS |
| role limitations emotional | 69.5 (41.6) | 73.9 (37.6) | 67.4 (41.6) | NS |
| mental health | 72.6 (17) | 72.7 (18) | 68.9 (19.2) | NS |
| bodily pain | 66.6 (23.8)† | 75.4 (25.3)*‡ | 68.5 (25.5)† | 0.001 |
| general health perception | 51.7 (21.6)† | 40.5 (22.3)*‡ | 52.5 (20.7)† | 0.000 |