Clinical and laboratory profiles of patients with Hirayama disease
| Serum IgE | p Value | ||
|---|---|---|---|
| Normal (n = 6) | Raised (n = 14) | ||
| Values are mean (SD) unless indicated. | |||
| *See text. | |||
| CMAP, compound muscle action potential. | |||
| Age (years) | 19.2 (1.2) | 21.1 (4.9) | NS |
| Age at onset (years) | 15.2 (2.0) | 16.0 (2.3) | NS |
| Male to female ratio | 5:1 | 14:0 | |
| Disease duration (years) | 4.0 (2.4) | 5.1 (6.0) | NS |
| Clinical grade* (median (range)) | 1.0 (1.0–2.0) | 2.0 (1.0–3.0) | 0.01 |
| History of atopy/allergy | 17% | 21% | NS |
| Serum IgE level (IU/ml) | 87 (43) | 899 (1165) | 0.01 |
| Radioallergosorbent test | |||
| Mite | 1.0 (1.2) | 2.6 (2.2) | 0.03 |
| House dust | 0.8 (1.3) | 2.7 (2.2) | 0.02 |
| Cedar pollen | 2.7 (2.2) | 2.4 (2.1) | NS |
| Soybean | 0 | 0.4 (0.9) | |
| Electrophysiology | |||
| Ulnar CMAP (mV) | 3.3 (2.0) | 2.8 (1.4) | NS |
| Active denervation on EMG | 2 of 4 | 9 of 13 | NS |