Baseline clinical characteristics of the patient groups under aciclovir therapy with and without concomitant corticosteroid administration
| Corticosteroid administration(n = 22) | No corticosteroid administration(n = 23) | Difference between the two groups* | |
|---|---|---|---|
| *Statistical differences between the two groups were evaluated by Fisher’s exact probability test and the Mann–Whitney U test. | |||
| CSF, cerebrospinal fluid; CT, cranial computed tomography; EEG, electroencephalogram; GCS, Glasgow Coma Scale; MRI, magnetic resonance imaging; NS, not significant; PLEDs, periodic lateralized epileptiform discharges. | |||
| (1) Male (%) | 64 | 52 | NS |
| (2) Age in years (minimum, mean, median, and maximum) | 17.0, 45.0, 42.0,77.0 | 20.0, 46.8, 47.0, 76.0 | NS |
| (3) Days after onset at initiation of aciclovir | |||
| (minimum, mean, median, and maximum) | 1.0, 5.9, 5.0, 13.0 | 3.0, 7.3, 7.0, 12.0 | NS |
| (4) GCS score at initiation of aciclovir | |||
| (minimum, mean, median, and maximum) | 3.0, 7.3, 7.0, 14.0 | 3.0, 7.5, 6.0, 14.0 | NS |
| (5) Initial and <maximum> leucocyte cell count(/μl) in CSF | 4, 184, 49, 1376<4, 187, 56, 1376> | 4,178, 65, 944<6, 178, 65, 944> | NS |
| (minimum, mean, median, and maximum) | |||
| (6) Initial and <maximum> CSF protein (mg/dl) | 28, 106, 81, 580 | 40, 132, 86, 410 | NS |
| (minimum, mean, median, and maximum) | <33, 107, 81, 580> | <40, 145, 86, 410> | |
| (8) Detection of lesion by initial CT (%) | 59 | 65 | NS |
| (9) Detection of lesion by initial MRI (%) | 91 | 78 | NS |
| (10) Detection of PLEDs on EEG (%) | 50 | 43 | NS |