Controls (n = 513) | Total PD (n = 580) | YOPD (n = 263) | Sporadic PD (n = 193) | FPD (n = 124) | |
---|---|---|---|---|---|
Values are n (%) unless specified. | |||||
FPD, familial Parkinson’s disease (index familial cases with one or more relative also affected by Parkinson’s disease); PD, Parkinson’s disease; YOPD, young onset Parkinson’s disease (onset before the age of 45 years) | |||||
Genotype | |||||
H1H1 | 290 (56.5) | 377 (65) | 177 (67.3) | 125 (64.8) | 75 (60.5) |
H1H2 | 188 (36.6) | 171 (29.5) | 69 (26.2) | 57 (29.5) | 45 (36.3) |
H2H2 | 35 (6.9) | 32 (5.5) | 17 (6.5) | 11 (5.7) | 4 (3.2) |
Allele frequency | |||||
H1 (%) | 74.9 | 79.7 | 80.4 | 79.5 | 78.6 |
H2 (%) | 25.2 | 20.3 | 19.6 | 20.5 | 21.4 |