Validity
| Hypothesised group differences for corresponding MSIS-29 scores in groups of EDSS, GNDS, and MS subtype | p Value |
|---|---|
| EDSS, Expanded Disability Status Scale; GNDS, Guy’s Neurological Disability Scale; MS, multiple sclerosis; MSIS-29, Multiple Sclerosis Impact Scale; PP, primary progressive; RR, relapsing–remitting; SP, secondary progressive. | |
| EDSS | |
| MSIS-29 score (EDSS 0.0–3.5) < MSIS-29 score (EDSS 4.0–6.0) | 0.001 |
| MSIS-29 score (EDSS 0.0–3.5) < MSIS-29 score (EDSS ⩾6.5) | 0.000 |
| MSIS-29 score (EDSS 4.0–6.0) < MSIS-29 score (EDSS ⩾6.5) | 0.000 |
| GNDS | |
| MSIS-29 score (GNDS <15) < MSIS-29 score (GNDS ⩾15) | 0.000 |
| MS subtype (physical) | |
| MSIS-29 score (RR) < MSIS-29 score (SP) | 0.001 |
| MSIS-29 score (RR) < MSIS-29 score (PP) | 0.001 |
| MSIS-29 score (SP) < MSIS-29 score (PP) | 0.584 |
| MS subtype (psychological) | |
| MSIS-29 score (RR) < MSIS-29 score (SP) | 0.052 |
| MSIS-29 score (RR) < MSIS-29 score (PP) | 0.195 |
| MSIS-29 score (SP) < MSIS-29 score (PP) | 0.706 |