Comparison of clinical characteristics of the different pathological patterns
| Immunopathological classification | ||||
|---|---|---|---|---|
| I(n = 17) | II(n = 34) | III(n = 15) | NA(n = 25) | |
| No significant differences were found when comparing patterns I–III for any of the clinical variables described (p>0.1). | ||||
| NA, non-active; PP, primary progressive ; PR, progressive relapsing; SP, secondary progressive; RR, relapsing remitting. | ||||
| EDSS at most recent follow up (median) | 3.0 | 3.0 | 3.0 | 3.5 |
| Range is 0–10 for all groups | ||||
| Duration in years of MS (median (range)) | 4.1 (1.0–14.1) | 4.5 (0.9–33.1) | 5.2 (1.2–15.7) | 5.2 (0.3–33.1) |
| Time from onset (first attack) to biopsy in months (median (range)) | 4 (0–113) | 2 (0–331) | 1.0 (0–42) | 4 (0–360) |
| Time from index attack to biopsy in months (median (range)) | 1.1 (0.2–5.6) | 1.1 (0.1–7.9) | 0.8 (0.2–2.6) | 1.5 (0.2–15.0) |
| Sex (n (%)) | ||||
| Male | 7 (41.2) | 16 (47.1) | 8 (53.3) | 12 (48) |
| Female | 10 (58.8) | 18 (52.9) | 7 (46.7) | 13 (52) |
| Most recent course classification (n (%)) | ||||
| RR | 9 (52.9) | 21 (61.8) | 5 (33.3) | 12 (48) |
| PR | 0 (0) | 1 (2.9) | 1 (6.7) | 1 (4) |
| SP with superimposed attacks | 3 (17.6) | 6 (17.6) | 1 (6.7) | 3 (12) |
| SP without superimposed attack | 0 (0) | 2 (5.9) | 1 (6.7) | 1 (4) |
| PP | 1 (5.9) | 0 (0) | 0 (0) | 1 (4) |
| Monophasic | 3 (17.6) | 3 (8.8) | 5 (33.3) | 6 (24) |
| Uncertain | 1 (5.9) | 1 (2.9) | 2 (13.3) | 1 (4) |