Factors associated with early seizures: bivariate analysis
| Variable | Patients without ES (n = 191) | Patients with ES (n = 11) | p Value | OR (95% CI) |
|---|---|---|---|---|
| Values are number of patients (%) (χ2 test with Yate’s correction if necessary or Fisher’s exact test), except for the neuroimaging results where they are median (range) (Mann-Whitney’s test). | ||||
| CI, confidence interval; IQCODE, Informant Questionnaire on Cognitive Decline in the Elderly; ES, early seizures; NA, not applicable; OR, odds ratio. | ||||
| Demographic data | ||||
| Age (years)* | 75 (42–100) | 76 (43–89) | 0.752 | |
| Male sex | 91 (47.6) | 6 (54.5) | 0.761 | 1.14 (0.43 to 2.98) |
| Past medical history | ||||
| Stroke | 30 (15.7) | 2 (18.2) | 0.687 | 1.16 (0.24 to 5.51) |
| Alcohol abuse | 37 (19.4) | 3 (27.3) | 0.458 | 1.38 (0.40 to 4.72) |
| Pre-existing cognitive status | ||||
| Pre-existing dementia | 31 (16.2) | 2 (18.2) | 1.000 | 1.11 (0.26 to 4.80) |
| IQCODE score* | 83 (78–130) | 85 (78–121) | 0.539 | |
| Stroke severity | ||||
| Orgogozo’s score at admission* | 70 (0–100) | 65 (15–100) | 0.520 | |
| Type of stroke | ||||
| Ischaemic | 169 (88.5) | 8 (72.8) | 0.141 | 0.83 (0.34 to 2.02) |
| Aetiology of ischaemic stroke | ||||
| Atheroma | 26 (13.6) | 1 (9.1) | 1.000 | 0.68 (0.09 to 5.06) |
| Cardioembolic | 46 (24.1) | 2 (18.2) | 1.000 | 0.77 (0.18 to 3.34) |
| Small vessel disease | 35 (18.3) | 2 (18.2) | 1.000 | 0.99 (0.23 to 4.30) |
| Other known cause | 4 (2.1) | 0 | NA | NA |
| Undetermined | 58 (30.4) | 3 (27.3) | 1.000 | 0.90 (0.26 to 3.13) |
| Location of the lesions (old and new) | ||||
| Superficial | 78 (40.9) | 3 (27.3) | 0.531 | 0.68 (0.19 to 2.37) |
| Deep | 127 (60.2) | 8 (45.5) | 1.000 | 1.34 (0.34 to 5.24) |
| Posterior fossa | 18 (9.4) | 1 (9.1) | 1.000 | 0.97 (0.13 to 7.09) |
| Location of the lesions (old) | ||||
| Superficial | 15 (7.8) | 1 (9.1) | 1.000 | 1. 16 (0.14 to 9.65) |
| Deep | 53 (27.7) | 6 (54.5) | 0.084 | 1.97 (0.69 to 5.58) |
| Posterior fossa | 10 (5.2) | 0 | NA | NA |
| Location of the lesions (new) | ||||
| Superficial | 74 (38.7) | 2 (1.8) | 0.214 | 0.47 (0.10 to 2.18) |
| Deep | 115 (60.2) | 5 (45.5) | 0.359 | 0.75 (0.25 to 2.24) |
| Posterior fossa | 18 (9.4) | 1 (9.1) | 1.000 | 0.96 (0.12 to 7.96) |
| Neuroimaging | ||||
| Leucoaraiosis score | 1 (0–3) | 2.5 (0–3) | 0.071 | |
| Cerebral atrophy score | 2 (0–3) | 2 (0–3) | 0.280 | |