Table 1

 Number of patients with two distinct ultrasound findings: one combining a hyperechogenic substantia nigra (SN) on at least one side with a regular echogenic lentiform nucleus (LN) on both sides and the other combining a hyperechogenic LN on one or both sides with a moderate or low echogenic SN. The first combination together with the clinical finding of “parkinsonism” reliably predicted IPD, whereas the second combination was indicative of an atypical parkinsonian syndrome

Echo pattern of the SN and the LNNo of patientsPositive predictive value
With Parkinson’s diseaseWith atypical parkinsonian syndromes
Hyperechogenic SN combined with regular echogenic LN5860.91
Hyperechogenic LN combined with moderate echogenic SN at best1280.96