Cognitive test scores (mean (SD)) prior to and during 12 weeks of donepezil therapy
| Baseline | 12 weeks | % Change | Wilcoxon’s signed rank test | |
|---|---|---|---|---|
| Wilcoxon’s signed rank test S values with significance levels are presented. | ||||
| Attention and executive functions (Stroop Color Word interference test and Trail Making Test, TMT B). | ||||
| Word fluency (Controlled Oral Word Association, COWA). | ||||
| CVLT, California Verbal Learning Test; MMSE, Mini-Mental State Examination; S/LTM short/long term memory. | ||||
| MMSE | 22.6 (4.3) | 23.5 (3.4) | 4.0 (16.4) | S = 11.5, NS |
| CVLT-STM | 2.0 (2.4) | 2.5 (2.3) | 25.0 (108.1) | S = 5, NS |
| CVLT-LTM | 2.1 (2.5) | 2.9 (3.7) | 38.1 (124.5) | S = 8.5, NS |
| TMT B (seconds) | 215.9 (82.9) | 227.5 (80.00) | 5.4 (32.6) | S = 11.5, NS |
| Stroop Interference | 15.9 (6.0) | 15.5 (5.7) | −2.5 (27.1) | S = −8, NS |
| COWA | 28.8 (13.4) | 30.3 (10.4) | 5.2 (42.2) | S = 5, NS |