Comparison of Alzheimer’s disease and control groups using one to one age matching
| Variable | AD (n = 23) | Normal (n = 23) | p Value |
|---|---|---|---|
| Values are mean (SD). | |||
| AD, Alzheimer’s disease; AVLT-recall, auditory verbal learning test–recall; Blocks, block design subtest; BVRT, Benton visual retention test; CFT-copy, complex figure test–copy; CFT-recall, complex figure test–recall; Cogstat, composite measure of cognitive impairment; COWA, controlled oral word association; CS, contrast sensitivity; FVA, far visual acuity; JLO, judgment of line orientation; NVA, near visual acuity; SFM, structure from motion; TMT-B, trail making test subtest B; UFOVTOT, total of subtests of the useful field of view task; y, years. | |||
| Demographics | |||
| Age (y) | 74.1 (6.1) | 74.1 (6.1) | 1.0000 |
| Education (y) | 15.2 (3.0) | 15.7 (2.2) | 0.1515 |
| Symptom duration (y) | 2.0 (1.6) | ||
| Cognitive tests | |||
| Cogstat | 294 (47) | 397 (43) | <0.0001 |
| AVLT-recall | 3.0 (2.5) | 10.3 (2.8) | <0.0001 |
| BVRT (errors) | 9.4 (3.2) | 5.1 (2.2) | <0.0001 |
| CFT-recall | 9.3 (4.7) | 15.7 (5.1) | 0.0005 |
| JLO | 23.0 (4.4) | 25.1 (4.5) | 0.2242 |
| Blocks | 23.4 (8.9) | 38.8 (10.6) | <0.0001 |
| CFT-copy | 29.1 (4.0) | 31.7 (3.5) | 0.0508 |
| TMT-B | 154 (81) | 82 (27) | <0.0001 |
| COWA | 33.2 (11.6) | 41.11 (9.4) | 0.0002 |
| Visual tests | |||
| NVA | 0.056 (0.070) | 0.022 (0.036) | 0.0179 |
| FVA | 0.034 (0.124) | −0.043 (0.129) | 0.0324 |
| CS | 1.66 (0.18) | 1.79 (0.16) | 0.0057 |
| SFM | 14.0 (8.3) | 10.4 (2.5) | 0.0723 |
| UFOVTOT (ms) | 1257 (231) | 778 (194) | <0.0001 |