Clinical detail of cases with and without cerebral amyloid angiopathy (CAA)
| CAA(n = 8) | No CAA(n = 80) | |
|---|---|---|
| Median (range) age in years | 58 (21–75) | 26.5 (0–79) |
| Cause of injury (n (%)) | ||
| Fall | 4 (50) | 29 (36) |
| Road traffic accident | 4 (50) | 45 (56) |
| Assault | 0 | 6 (8) |
| Median (range) survival time in hours | 25.5 (16–240) | 48 (4–576) |
| Median (range) contusion index | 19 (0–54) | 14.5 (0–46) |
| Aβ plaques (n (%)) | 7 (88) | 17 (21) |
| APOE genotype (n (%)) | ||
| E2,2 | 0 | 2 (2) |
| E2,3 | 0 | 7 (9) |
| E2,4 | 0 | 4 (5) |
| E3,3 | 1 (12) | 38 (48) |
| E3,4 | 3 (38) | 27 (34) |
| E4,4 | 4 (50) | 2 (2) |
| APOE allele frequency (n/N (%)) | ||
| ε2 | 0 | 15/160 (9) |
| ε3 | 5/16 (31) | 110/160 (69) |
| ε4 | 11/16 (69) | 35/160 (22) |