Table 2

Univariate risk factors for sudden cardiac death (life table analysis): RDNS sudden cardiac deaths (n = 21) v all other deaths + alive (n = 441)

Risk factor	HR	95% CI	p Value
*Mean over time.
†ECG 1, ECG diagnostic of acute myocardial infarction or evolving diagnostic; ECG 2, ECG with left bundle branch block or electronically paced complexes.
Significant values in bold.
CASS, composite autonomic severity score; CI, confidence interval; HDLC, high density lipoprotein cholesterol; HR, hazard ratio; JTc, corrected JT interval; QTc, corrected QT interval; RDNS, Rochester diabetic neuropathy study.
Age (10 years), at last evaluation	2.20	1.36 to 3.56	0.001
Type of diabetes mellitus	4.54	1.06 to 19.52	0.042
Renal disease, at last evaluation	1.64	0.64 to 4.25	0.306
FPG (10 mg/dl (0.56 mmol/l))*	1.01	0.92 to 1.11	0.822
Glycosylated Hb (10%)*	0.96	0.77 to 1.20	0.717
Calculated HbA1c (10%)*	0.94	0.66 to 1.34	0.717
HDLC (10 mg/dl (0.26 mmol/l))*	0.50	0.29 to 0.87	0.014
Cholesterol (10 mg/dl (0.26 mmol/l))*	0.95	0.82 to 1.09	0.434
Triglycerides (10 mg/dl (0.11 mmol/l))*	1.01	0.98 to 1.05	0.362
Creatinine (mg/dl)*	1.88	1.33 to 2.65	<0.001
Microalbuminuria (1000 mg/24 h)*	2.38	1.50 to 3.76	<0.001
Total proteinuria (1000 mg/24 h)*	1.69	1.24 to 2.30	<0.001
Systolic blood pressure (10 mm Hg)*	1.35	1.00 to 1.82	0.047
Smoking (10 pack years), at last evaluation	1.17	0.97 to 1.39	0.094
Calcification of vessels in foot, at last evaluation	6.73	1.23 to 36.86	0.028
ECG 1*†	6.27	2.23 to 17.62	0.001
ECG 2*†	7.47	2.43 to 22.99	<0.001
ECG 1 or 2*	10.59	4.06 to 27.64	<0.001
JTc (ms)*	1.01	0.99 to 1.03	0.589
QTc (ms)*	1.02	1.01 to 1.04	0.005
CASS total (points)*	1.52	1.20 to 1.91	<0.001
CASS adrenergic (points)*	2.06	1.06 to 4.00	0.032
CASS sudomotor (points)*	1.10	0.39 to 3.11	0.860
CASS cardiovagal (points)*	2.50	1.37 to 4.55	0.003
Nephropathy stage*	2.76	1.60 to 4.76	<0.001
Neuropathy stage*	0.84	0.44 to 1.59	0.589