Sensitivities and specificities of the tests from the brief executive assessment for identifying a cognitive deficit caused by ischaemic leukoaraiosis
| Cut off score | All subjects | Subjects with MMSE >27 | ||||||
|---|---|---|---|---|---|---|---|---|
| Sens % | Spec % | Correctly assigned (%) | AUC (95% CI) | Sens % | Spec % | Correctly assigned (%) | ||
| Optimal cut off scores were identified assuming a minimum specificity of 75%. MMSE, mini-mental state examination; sens, sensitivity; spec, specificity; WAIS-R, Wechsler adult intelligence scale–revised. | ||||||||
| General/clinical | ||||||||
| MMSE | 28 | 63 | 76 | 67 | 0.76 (0.62 to 0.89) | |||
| Brief assessment | ||||||||
| Trail making B | 117 s | 75 | 76 | 76 | 0.87 (0.77 to 0.96) | 83 | 75 | 79 |
| Trail making B corrected | 78 s | 81 | 82 | 82 | 0.87 (0.76 to 0.97) | 83 | 88 | 85 |
| Trail making B−A | 56 s | 88 | 76 | 84 | 0.85 (0.74 to 0.97) | 83 | 81 | 82 |
| FAS verbal fluency | 27 | 47 | 76 | 57 | 0.72 (0.58 to 0.87) | 33 | 75 | 53 |
| WAIS-R digit symbol | 37 | 91 | 76 | 86 | 0.95 (0.89 to 1.00) | 89 | 81 | 85 |
| WAIS-R digit span back | 4 | 47 | 76 | 57 | 0.71(0.56 to 0.86) | 39 | 81 | 59 |
| Discriminant function | 0.57 | 88 | 88 | 88 | 0.95 (0.89 to 1.00) | 89 | 94 | 91 |