Test | Mean scores on treatment (SD) | Mean scores on placebo (SD) | Treatment effect (SE) | p value | Adjusted p value* | |||||
---|---|---|---|---|---|---|---|---|---|---|
ADAScog, Alzheimer’s disease rating scale, cognitive scale; MDRS, Mattis Dementia Rating Scale ; MMSE, Mini Mental Status; CGI, Clinical Global Impression. *Adjusted for multiple comparisons using Hommel method. | ||||||||||
ADAScog | 22.5 (6.9) | 24.4 (9.4) | −1.9 (1.4) | 0.18 | 0.54 | |||||
MMSE | 24.5 (3.2) | 22.5 (4.7) | 2.0 (0.61) | 0.0044 | 0.018 | |||||
MDRS | 108.3 (17.13) | 108.5 (18.2) | −0.2 (1.9) | 0.98 | 0.98 | |||||
MDRS attention | 31.0 (5.1) | 31.1(5.2) | ||||||||
MDRS initiative | 25.9 (6.3) | 25.5 (7.0) | ||||||||
CGI | 3.58 (0.77) | 3.95 (0.85) | −0.37 (NA) | 0.0056 | 0.022 |