Table 2

 Summary of multiple linear regression analyses examining a global measure of cognitive abilities as a function of the e4 allele (model 1), and both the e4 allele and a measure of amyloid load (model 2). All models controlled for age, sex, and education

Outcome measure termsModel 1Model 2
Estimate (SE)p valueEstimate (SE)p value
GC, Global Cognition.
GC
    e4 allele−0.432 (0.210)0.04−0.176 (0.214)0.41
    Amyloid load−0.145 (0.044)0.001