Table 1

 Demographics and baseline and 3-month cognitive data

PD, n = 22PDD, n = 27DLB, n = 11Comparison of baseline characteristics across groups
ChEIs, cholinesterase inhibitors; CRT, choice reaction time; CRT ACC, CRT response accuracy; DLB, dementia with Lewy bodies; DPIC RT, delayed picture recognition reaction time; DVIG RT, digit vigilance reaction time; MMSE, Mini-Mental State Examination; NPI, Neuropsychiatric Inventory; NWM RT, numeric working memory reaction time; PD, Parkinson’s disease; PDD, Parkinson’s disease with dementia; RDS, reverse digit span; SRT, simple reaction time; UPDRS, Unified Parkinson’s Disease Rating Scale; VAS, Visual Analogue Scale.
Values are mean (SD).
*Analysis of variance results.
†χ2 results.
‡Kruskal–Wallis results.
Age (years)78.1 (6.4)72.6 (5.2)76.4 (6.8)F2,57 = 5.282, p = 0.008*
Sex, M:F17:519:87:4χ2 = 0.712, p = 0.700†
Disease duration (years)5.0 (5.1)9.4 (6.0)2.8 (1.7)χ2 = 19.339, p<0.001‡
No taking levodopa at baseline14271χ2 = 31.429, p<0.001†
No taking ChEIs at baseline02310χ2 = 42.560, p<0.001†
UPDRS III at baseline32.6 (9.5)42.0 (13.2)34.3 (12.7)F2,57 = 4.185, p = 0.020*
Baseline SRT (ms)401 (94)696 (564)575 (249)χ2 = 11.709, p = 0.003‡
SRT 3 months (ms)411 (134)855 (671)540 (144)
Baseline CRT (ms)582 (108)1209 (906)1055 (560)χ2 = 21.890, p<0.001‡
CRT 3 months (ms)579 (128)1245 (639)1286 (1009)
Baseline CRT ACC (%)96.1 (6.5)85.8 (14.5)85.1 (13.2)χ2 = 13.306, p = 0.001‡
CRT ACC 3 months (%)96.1 (4.3)88.1 (13.2)81.5 (18.8)
Baseline NWM RT (ms)1268 (1091)2966 (2609)4255 (4272)χ2 = 15.203, p<0.001‡
NWM RT 3 months (ms)932 (258)3229 (2437)4313 (2581)
Baseline DVIG RT (ms)516 (75)680 (140)697 (124)F2,57 = 14.579, p<0.001*
DVIG RT 3 months (ms)526 (92)751 (205)647 (91)
Baseline DPIC RT (ms)1384 (1022)2723 (2371)3550 (3407)χ2 = 12.757, p = 0.002‡
DPIC RT 3 months (ms)1123 (308)2658 (1995)4279 (3584)
Baseline RDS6.2 (2.0)3.9 (1.8)3.4 (2.3)F2,57 = 11.102, p<0.001*
RDS 3 months5.4 (1.5)3.7 (2.1)3.4 (1.4)
Baseline VAS66.6 (12.6)46.9 (16.0)58.6 (17.4)F2,57 = 10.429, p<0.001*
VAS 3 months68.2 (16.5)48.2 (16.4)59.8 (14.1)
Baseline MMSE25.6 (2.2)20.7(4.8)19.5 (3.6)F2,57 = 13.641, p<0.001*
MMSE 3 months26.9 (2.5)19.7 (5.2)18.6 (4.6)
Baseline NPI5.6 (11.0)14.9 (15.1)11.9 (12.1)χ2 = 9.025, p = 0.011‡
NPI 3 months2.5 (5.4)9.6 (15.4)8.4 (9.6)