Demographic, surgical, and baseline neuropsychological data for patients and control subjects
| Variable | Group | Critical value | |
|---|---|---|---|
| Controls (n = 50), mean (SD) | CABG (n = 85), mean (SD) | ||
| BNT, Boston Naming Test (max = 60); COWAT, Controlled Oral Word Association Test; CPB time, cardiopulmonary bypass time; CVLT, California Verbal Learning Test; DSym, Digit Symbol subtest of the Wechsler Adult Intelligence Scale-Revised (raw score); FSIQ, predicted Full Scale IQ (National Adult Reading Test-Revised); ICU stay, postoperative hours spent in intensive care unit; MCPP, mean cerebral perfusion pressure; Mflow, mean blood flow rate; PegsRL, Purdue Pegboard (number of pegs placed with right and left hands simultaneously); SD, standard deviation; %SDFR, short delay free recall [(SDFR/trial 5)×100]; TMT B/A, Trail Making Test (seconds taken to complete part B/seconds taken to complete part A). | |||
| Continuous data analysed using independent groups t tests (two tailed), df = 133; categoric data analysed using χ2 test, df = 1. | |||
| *p<0.01. | |||
| Demographic | |||
| Age (years) | 68.0 (7.9) | 65.0 (9.3) | t = −1.88 |
| Education (years) | 10.2 (1.7) | 10.2 (2.8) | t = 0.06 |
| Sex (% male/female) | 68.0/32.0 | 77.6/22.4 | χ2 = 1.53 |
| Surgical | |||
| Grafts | – | 2.4 (0.8) | |
| %Hypothermic/%normothermic | – | 49.4/50.6 | |
| CPB time (min) | – | 43.0 (15.6) | |
| MCPP (mm Hg) | – | 42.0 (5.6) | |
| Mflow (l/min) | – | 3.8 (0.4) | |
| Perfusionist interventions | – | 5.7 (2.9) | |
| ICU stay (h) | – | 32.3 (19.7) | |
| Neuropsychological | |||
| Predicted FSIQ | 102.5 (9.3) | 101.4 (8.8) | t = −0.67 |
| CVLT %SDFR | 80.8 (15.8) | 83.6 (19.6) | t = 0.39 |
| CVLT recognition | 14.3 (1.8) | 14.3 (1.9) | t = 0.92 |
| BNT | 55.1 (4.1) | 55.3 (3.7) | t = 0.11 |
| TMT B/A | 2.5 (0.6) | 2.7 (1.1) | t = 0.97 |
| COWAT | 36.5 (11.5) | 36.0 (9.1) | t = −0.28 |
| DSym | 42.4 (8.8) | 39.2 (10.3) | t = 0.07 |
| PegsRL | 9.9 (1.9) | 9.3 (2.1) | t = −1.78 |
| Mood | |||
| Depression | 3.1 (5.0) | 5.2 (6.7) | t = 1.98 |
| Anxiety | 3.3 (4.6) | 6.6 (7.1) | t = 3.20* |
| Stress | 6.3 (6.6) | 9.2 (8.8) | t = 1.97 |