Epilepsy syndromes in early life
| Syndrome | Age of onset | Clinical | EEG |
|---|---|---|---|
| GTCS, generalised tonic-clonic seizure; MJ, myoclonic jerk; SW, spike wave. | |||
| Benign idiopathic neonatal seizures | 2–7 days (“5th day fits”) | Partial/clonic/apnoeic | Trace pointu alternans (75%) |
| Early myoclonic epilepsy | First month of life | Myoclonus, partial motor, tonic spasms | Burst suppression |
| Early infantile epileptic encephalopathy (Otohara syndrome) | 1–3 months | Tonic spasms; may be focal motor, MJ, GTCS | Burst suppression |
| Severe myoclonic epilepsy of infancy (Dravet syndrome) | Within first year | Febrile → afebrile seizures, myoclonus, atypical absences | Generalised SW photosensitivity (40%) |
| West syndrome | 4–7 months | Infantile spasms | Hypsarrhythmia |