Table 2

 Epilepsy syndromes in early life

SyndromeAge of onsetClinicalEEG
GTCS, generalised tonic-clonic seizure; MJ, myoclonic jerk; SW, spike wave.
Benign idiopathic neonatal seizures2–7 days (“5th day fits”)Partial/clonic/apnoeicTrace pointu alternans (75%)
Early myoclonic epilepsyFirst month of lifeMyoclonus, partial motor, tonic spasmsBurst suppression
Early infantile epileptic encephalopathy (Otohara syndrome)1–3 monthsTonic spasms; may be focal motor, MJ, GTCSBurst suppression
Severe myoclonic epilepsy of infancy (Dravet syndrome)Within first yearFebrile → afebrile seizures, myoclonus, atypical absencesGeneralised SW photosensitivity (40%)
West syndrome4–7 monthsInfantile spasmsHypsarrhythmia