Cognitive and motor change between baseline and two years in patient groups, according to baseline motor subtype
| Group (n) | Controls (n = 38) | PD (n = 35) | PDD (n = 24) | DLB (n = 31) | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Values are shown as means (SD). IND, indeterminate subtype. Negative numbers represent a worsening and positive numbers represent an improvement, compared with baseline values. | ||||||||||
| MMSE | −0.3 (2.0) | −0.2 (2.9) | −4.5 (7.0) | −3.9 (5.2) | ||||||
| CAMCOG | 1.1 (6.9) | −1.8 (7.8) | −11.0 (14.2) | −9.5 (9.9) | ||||||
| UPDRS III | −1.6 (2.5) | −5.1 (13.4) | −9.7 (13.8) | −11.3 (14.6) | ||||||
| Phenotype (n) | IND (5) | PIGD (14) | TD (16) | IND (2) | PIGD (21) | TD (1) | IND (6) | PIGD (22) | TD (3) | |
| MMSE (n) | 0.2 (1.9) n = 5 | −1.8 (3.3) n = 14 | 1.1 (2.0) n = 16 | −1.0 (0.0) n = 2 | −5.1 (7.3) n = 20 | 0.0 n = 1 | −5.3 (4.6) n = 6 | −4.3 (4.9) n = 17 | 1.3 (6.5) n = 3 | |
| CAMCOG (n) | 1.0 (2.8) n = 5 | −6.1 (9.7) n = 14 | 1.2 (4.9) n = 16 | 1.5 (7.8) n = 2 | −11.7 (14.1) n = 13 | −27.0 n = 1 | −10.0 (9.8) n = 5 | −11.1 (7.8) n = 7 | −5.0 (16.5) n = 3 | |
| UPDRS III (n) | 1.0 (15.0) n = 5 | −8.9 (14.3) n = 14 | −3.6 (11.9) n = 16 | −10.0 (7.1) n = 2 | −9.8 (14.9) n = 18 | −7.0 n = 1 | −8.3 (12.1) n = 6 | −10.6 (16.7) n = 11 | −19.7 (11.2) n = 3 | |