Table 3 Initial clinical, imaging and autopsy diagnosis

Case No	Clinical diagnosis	No of core features of DLB	Visual rating diagnosis	Semiquantitative diagnosis	Neuropathological diagnosis
1	AD	0	Abn	Abn	DLB+AD
2	DLB	3	Abn	Abn	DLB
3	DLB	2	N	Abn	DLB
4	DLB	2	Abn	Abn	DLB+AD+CVD
5	CBD	1	Abn	N	DLB+AD
6	DLB	2	Abn	Abn	DLB
7	DLB	2	Abn	Abn	DLB+CVD
8	DLB	3	Abn	Abn	DLB
9	AD	0	N	N	AD+CVD
10	AD	0	N	N	AD+CVD+metastatic carcinoma
11	DLB	2	Abn	N	AD+CVD
12	DLB	2	N	N	AD
13	DLB	2	N	N	CBD
14	DLB	2	N	N	AD
15	AD	1	N	N	Unspecified pathology
16	AD	0	N	N	AD +CVD
17	DLB	1	Abn	N	FTLD
18	DLB	2	N	N	AD
19	DLB	2	N	N	AD+CVD
20	AD	0	N	N	AD+CVD

Abn, abnormal scan; AD, Alzheimer’s disease; CBD, cortico-basal degeneration; CVD, cerebrovascular disease; DLB, dementia with Lewy bodies; FTLD, fronto-temporal lobar degeneration; N, normal scan.
In the visual rating there was complete agreement between all three raters for 15 cases. In the remaining five cases there was a 2:1 split. In two of these cases the dissent related to scores of 0 or 1, therefore having no effect on the assignment of the scan as normal or abnormal. The three cases where disagreement potentially affected the assignment of the scan were case Nos 1, 7 and 12.