Table 1 Clinical characteristics of patients with pneumococcal and meningococcal meningitis
Pneumococcal patients (n = 79)Meningococcal patients (n = 76)p Value*
Presentation
    Glasgow Coma Scale score (mean (SD))11 (3)12 (3)0.03
    Coma (n (%))10 (13)8 (11)0.62†
    Median heart rate (bpm) (mean (SD))100 (16.8)88 (18.9)<0.001
    Diastolic blood pressure <60 mm Hg (n (%))8 (10)16 (21)0.12
    Focal cerebral deficits‡ (n (%))18 (23)11 (14)0.22†
    Cranial nerve palsies (n (%))16 (20)5 (7)0.02†
Laboratory results on admission
    CSF leucocyte count (×103 cells/mm3) (mean (SD))18 (25)19 (28)0.42
    CSF protein level (g/l) (mean (SD))4.3 (2.7)4.9 (3.4)0.43
    CSF glucose level (mg/dl) (mean (SD))1.2 (1.4)1.4 (1.9)0.62
    Positive blood culture (n (%))54 (68)56 (74)0.99†
Focal neurological abnormalities at discharge
    Focal cerebral deficits (n (%))4 (5)2 (3)0.68†
    Cranial nerve palsies (n (%))22 (28)9 (12)0.02†
Glasgow Outcome Scale score 3 or 4/5 at discharge23/563/73<0.001†
Time between illness and cognitive testing (months) (mean (SD))54.7 (44.0)68.8 (49.4)0.10
  • *Two tailed p value of U test; †χ2 test.

  • ‡Aphasia, monoparesis or hemiparesis.