| Neuropsychological measure | Pneumococcal patients (n = 79) | Meningococcal patients (n = 76) | p Value* | ||
| P vs M | P vs C | M vs C | |||
| Intelligence | |||||
| Visuospatial reasoning (GIT) | 50.5 (10.9) | 50.0 (11.4) | 0.77 | 0.78 | 0.97 |
| Verbal reasoning (GIT) | 50.8 (10.5) | 51.2 (10.6) | 0.79 | 0.62 | 0.45 |
| Attention/executive functioning | |||||
| Stroop Colour–Word Card | 44.1 (13.8) | 45.9 (11.1) | 0.39 | 0.01 | 0.04 |
| TMT part B | 40.4 (17.4) | 45.6 (12.6) | 0.04 | 0.00 | 0.05 |
| Numerical ability (GIT) | 46.8 (10.4) | 51.8 (10.5) | <0.01 | 0.06 | 0.31 |
| Category Fluency | 50.9 (10.8) | 48.9 (12.6) | 0.30 | 0.63 | 0.55 |
| Letter Fluency | 47.4 (10.7) | 48.1 (7.9) | 0.67 | 0.14 | 0.21 |
| WCST categories | 48.0 (13.4) | 46.4 (11.0) | 0.42 | 0.40 | 0.07 |
| WCST errors | 49.8 (10.8) | 48.1 (10.5) | 0.34 | 0.92 | 0.28 |
| WCST perseverative errors | 46.9 (12.2) | 46.3 (10.2) | 0.74 | 0.11 | 0.03 |
| Memory | |||||
| RMBT immediate recall | 50.4 (9.2) | 50.6 (12.1) | 0.92 | 0.78 | 0.73 |
| RMBT % retained | 48.5 (13.0) | 46.3 (13.3) | 0.33 | 0.30 | 0.04 |
| WMS immediate recall | 47.0 (14.2) | 48.6 (11.8) | 0.48 | 0.16 | 0.46 |
| WMS % retained | 45.7 (15.9) | 51.5 (9.3) | <0.01 | 0.06 | 0.36 |
| AVLT immediate recall | 48.2 (10.2) | 48.8 (10.2) | 0.72 | 0.10 | 0.21 |
| AVLT % retained | 48.8 (13.6) | 48.0 (13.0) | 0.81 | 0.66 | 0.48 |
| Psychomotor functions | |||||
| TMT part A | 43.0 (14.6) | 47.7 (11.3) | 0.03 | 0.00 | 0.37 |
| Stroop Word-Card | 43.9 (14.4) | 45.6 (13.3) | 0.46 | 0.00 | 0.03 |
| Stroop Colour-Card | 43.2 (11.1) | 43.7 (12.3) | 0.80 | 0.00 | 0.00 |
| SRT dominant hand | 40.6 (18.0) | 44.8 (13.3) | 0.12 | 0.00 | 0.02 |
| SRT non-dominant hand | 43.3 (17.2) | 45.9 (11.2) | 0.31 | 0.02 | 0.05 |
| Two choice reaction time | 47.2 (17.2) | 48.4 (12.1) | 0.65 | 0.31 | 0.44 |
| Speed score | 45.3 (8.8) | 47.5 (6.7) | 0.08 | <0.01 | 0.06 |
| No of impaired tests | 2.2 (2.3) | 1.6 (2.1) | 0.10 | <0.01 | <0.01 |
AVLT, Rey Auditory Verbal Learning Test; GIT, Groningen Intelligence Test; RBMT, Rivermead Behavioural Memory Test; SRT, Simple Reaction Time; TMT, Trail Making Test; WCST, Wisconsin Card Sorting Test; WMS, Wechsler Memory Scale.
Values are mean (SD).
*Two tailed p value of t test: comparison of pneumococcal (P) and meningococcal (M) patients; comparison of pneumococcal (P) patients and controls (C); comparison of meningococcal (M) patients and controls (C).