Median values (standard deviations) of clinical disability (Kurtzke’s EDSS and functional systems) in the whole multiple sclerosis group and in the different disease courses: primary progressive; relapsing remitting; secondary progressive; progressive
| MS (n = 84) | PP (n = 13) | RR (n = 43) | SP (n = 28) | SP v PP | Progressive v RR | |
|---|---|---|---|---|---|---|
| EDSS, Expanded Disability Status Scale; F, female; FS, functional system; M, male; MS, multiple sclerosis; NS, not significant; PP, primary progressive; progressive, pooled secondary progressive and primary progressive; RR, relapsing remitting; SP, secondary progressive. | ||||||
| p Values of differences (right column) represent contrasts by Mann–Whitney U test. | ||||||
| Age (years) | 37.8 (9.9) | 43.8 (6.9) | 33.7 (9.4) | 41.0 (9.5) | NS | <0.001 |
| F/M | 51/33 | 5/8 | 28/15 | 18/10 | NS | NS |
| MS duration (months) | 90.1 (77.2) | 54.5 (65.4) | 85.1 (71.3) | 112.7 (85.4) | 0.04 | NS |
| EDSS | 3.5 (1–8) | 5.5 (2–6.5) | 3 (1–6) | 5 (2.5–8) | NS | <0.001 |
| Pyramidal FS | 3 (0–5) | 3 (1–4) | 2 (0–5) | 3 (1–5) | NS | <0.001 |
| Brain stem FS | 1 (0–3) | 2 (0–3) | 1 (0–3) | 2 (0–3) | NS | NS |
| Sensory FS | 1 (0–3) | 2 (0–3) | 1 (0–3) | 2 (0–3) | NS | 0.03 |
| Visual FS | 0 (0–6) | 0 (0–3) | 0 (0–6) | 1 (0–6) | NS | 0.03 |