Table 2 Polysomnographical data of 46 patients with Chiari malformation divided into three age groups
Characteristic⩽18 years (n = 20)19–30 years (n = 10)⩾31 years (n = 16)p Value
Polysomnography
    Total sleep time481.9 (21.5)395.8 (30.2)313.7 (21)<0.001
    Sleep onset latency20.8 (4.3)23.0 (7.7)18.7 (6.3)NS
    % Sleep efficiency89.1 (3.0)74.8 (7.8)76.8 (3.6)0.05
    % Stage 247.0 (2.1)55.2 (1.9)54.3 (3.6)NS
    % SWS26.2 (1.4)18.9 (0.9)18.8 (1.7)<0.005
    % REM19.5 (1.3)16.3 (2.3)11.5 (1.5)<0.01
SAS diagnosis (%)
    SAS6060810.05
    OSAS354069<0.01
    Severe OSAS0031<0.05
    CSAS252013NS
    Severe CSAS006NS
Respiratory events
    AHI2.6 (0.5)5.64 (1.6)26.4 (6.6)<0.001
    OAI0.2 (0.07)0.48 (0.2)6.7 (2.4)<0.005
    HI1.6 ( 0.4)3.84 (1.5)16.4 (4.6)<0.005
    CAI0.8 (0.2)1.31 (0.8)3.3 (1.7)NS
O2 saturation
    O2 mean saturation97.0 (0.2)96.15 (0.4)92.9 (0.9)<0.001
    O2 min saturation84.7 (2.1)89.08 (1.6)80.7 (2.7)NS
    TTS (%) with SaO2 <90%1.0 (0.5)0.4 (0.3)13.1 (5.3)0.05
  • AHI, apnoea hypopnoea index; CAI, central apnoea index; CSAS, central sleep apnoea syndrome; HI, hypopnoea index; OAI, obstructive apnoea index; OSAS, obstructive sleep apnoea syndrome; REM, rapid eye movements; SAS, sleep apnoea syndrome; SWS, slow wave sleep.

  • Results are expressed as mean (SEM) or %.

  • TTS (%) with SaO2 <90%, mean (SEM): percentage of sleep time spent with SaO2 below the threshold of 90%. We used this latter criterion as an indicator of SAS severity. The value for each patient corresponds to drops of SaO2 below 90% following apnoeic events with return to normal SaO2 after the drop. It also corresponds to long sustained desaturations below 90% for two patients who also presented with central alveolar hypoventilation.

  • Analysis of the effect of age group on continuous variables was tested by one way ANOVA with corresponding p significance values. Pearson χ2 tests were used for dichotomous variables.