Table 2 Demographics and clinical features of Irish patients diagnosed with ALS in incident and prevalent cohorts
Incident cohort (n = 465)*Prevalent cohort (n = 200)†
Median age (y)66.061.8
Sex (M:F) (%)268 (57.6):197 (42.4)120 (60.0):80 (40.0)
Limb:bulbar:generalised onset (%)268 (57.6): 164 (35.3): 33 (7.1)137 (68.5): 63 (31.5): 0
Patients younger than 55 y (%)93 (20.0)67 (33.5)
Patients older than 65 y (%)244 (52.5)74 (37.0)
Family history of ALS (%)29 (6.2)11 (10.5)
Second diagnosis of FTD (%)32 (6.9)12 (6.0)
Mean diagnostic delay (months)13.022.7
Median survival (months)16.4120.9

  • *1995–1997 and 2002–2004 cohorts combined.

  • †On 31 December 2003.

  • ALS, amyotrophic lateral sclerosis; FTD, frontotemporal dementia.