RBD (n = 21) | No RBD (n = 15) | Regression RBD main effect (SE) | p Value | |
Medication on/off differences | ||||
UPDRS II (% change on/off) | 7.0 (15.3) | 17.2 (27.8) | −0.51 (1.43) | 0.72 |
UPDRS III (% change on/off) | 16.2 (18.9) | 34.8 (28.2) | −18.5 (9.0) | 0.049 |
Purdue (% change on/off) | 4.8 (12.8) | 14.8 (20.4) | −6.9 (6.3) | 0.29 |
Up and go (% change on/off) | 9.8 (18.3 | 10.3 (17.5) | −0.70 (6.9) | 0.92 |
Alternate Tap Test (% change) | 7.7 (19.4) | 16.7 (15.9) | −7.2 (7.0) | 0.31 |
Motor complications of therapy | ||||
History of dyskinesia (yes:no) | 4:17 (19%) | 5:10 (33%) | 0.67 (1.44) | 0.64 |
UPDRS IV (dyskinesia total) | 0.52 (1.37) | 0.73 (1.28) | 0.06 (0.41) | 0.89 |
History of fluctuations (yes:no) | 5:16 (24%) | 5:10 (33%) | 2.0 (1.5) | 0.19 |
UPDRS IV (fluctuations total) | 0.62 (1.16) | 1.1 (1.5) | −0.20 (0.42) | 0.65 |
Quantitative motor testing | ||||
Purdue Peg “off” (No of pegs) | 7.4 (2.1) | 8.4 (2.0) | −1.11 (0.64) | 0.096 |
Alternate Tap “off” (No of taps) | 132.5 (30.4) | 138.1(26.7) | −5.8 (11.0) | 0.60 |
Up and go “off” (s) | 10.3 (6.4) | 8.8 (2.5) | 1.4 (1.8) | 0.45 |
Data for continuous variables are presented as mean (SD).
RBD, REM sleep behaviour disorder; UPDRS, Unified Parkinson Disease Rating Scale.