| Population prevalence (%) | n | mTBI (n (%)) | n | Controls (n (%)) | p Value* | |
| Affective disorders | ||||||
| Major depression | 16.6 | 77 | 19 (24.7) | 83 | 15 (18.1) | 0.308 |
| Dysthymia | 2.5 | 77 | 1 (1.3) | 83 | 1 (1.2) | 1.000‡ |
| Any affective disorder† | – | 77 | 20 (26.0) | 83 | 16 (19.3) | 0.311 |
| Anxiety disorder | ||||||
| Panic disorder | 4.7 | 77 | 11 (14.3) | 83 | 4 (4.8) | 0.056‡ |
| PDLS attacks | – | 77 | 3 (3.9) | 83 | 4 (4.8) | 1.000‡ |
| Agoraphobia | 1.4 | 76 | 9 (11.8) | 83 | 9 (10.8) | 0.843 |
| Social phobia | 12.1 | 76 | 9 (11.8) | 83 | 6 (7.2) | 0.320 |
| OCD | 1.6 | 75 | 7 (9.3) | 83 | 7 (8.4) | 0.842 |
| PTSD | 6.8 | 76 | 17 (22.4) | 83 | 12 (14.5) | 0.197 |
| GAD | 5.7 | 77 | 9 (11.8) | 83 | 12 (14.5) | 0.627 |
| Any anxiety disorder† | – | 77 | 32 (41.6) | 83 | 29 (34.9) | 0.389 |
| At least one disorder† | – | 77 | 35 (45.5) | 83 | 33 (39.8) | 0.467 |
| Substance use disorders | ||||||
| Alcohol abuse | 13.2 | 76 | 16 (21.1) | 83 | 21 (25.3) | 0.527 |
| Alcohol dependence | 5.4 | 76 | 10 (13.2) | 83 | 12 (14.5) | 0.813 |
| Marijuana abuse | 4.0 | 76 | 11 (14.5) | 83 | 12 (14.5) | 0.998 |
| Marijuana dependence | 4.0 | 76 | 8 (10.5) | 83 | 9 (10.8) | 0.948 |
| Any substance use disorder† | – | 76 | 20 (26.3) | 83 | 24 (28.9) | 0.714 |
Disorder, Affective, Anxiety and Substance use disorders were diagnosed using the Mini-International Neuropsychiatric Interview.
Panic disorder includes those with/without agoraphobia,
Agoraphobia is agoraphobia without panic disorder.
At least one diagnosis denotes the number of individuals who meet criteria for at least one preinjury affective or anxiety disorder.
Any substance use disorder denotes at least one preinjury substance disorder.
*χ2 analyses.
†Individual MINI diagnoses were grouped to form each category.
‡Fisher’s exact test.
GAD, general anxiety disorder; mTBI, mild traumatic brain injury; OCD, obsessive compulsive disorder; PDLS, panic disorder limited symptom; PTSD, post-traumatic stress disorder.