Presentation of dystonia | |||
Blepharospasm (n = 124) | Cervical dystonia (n = 73) | Focal hand dystonia (n = 26) | |
Age, years (SD) | 70.7 (8.9)† | 60 (13) | 55.2 (11.6) |
Sex, male/female | 30/94 | 24/49 | 14/12 |
Age of onset, years (SD) | 55.9 (10.7)‡ | 41.7 (13.9) | 39.1 (12.6) |
Period of follow-up, years (SD) | 14.9 (4.9) | 16.3 (5.0) | 14.8 (4.5) |
No of patients (%) who | 58 (47%)* | 17 (23%) | 10 (38%) |
experienced spread | |||
Spread to only one body site | |||
No of patients (%) | 46 (37) | 13 (18) | 6 (23) |
Age of spread, years (SD) | 59.9 (10.6)§ | 50.6 (11.3) | 52.4 (11.1) |
Time to spread, years (SD) | 4.5 (5.6)¶ | 9.3 (8.5) | 14.8 (11.6) |
Spread to a second body site | |||
No of patients (%) | 12 (10) | 4 (5) | 4 (15) |
Age of spread, years (SD) | 65.3 (8.5) | 48 (4.0) | 56.2 (6.6) |
Time from 1st to 2nd spread, years (SD) | 6.3 (4.5) | 8 (2.0) | 2.7 (3.0) |
Chi square (2 × 3): *p<0.001.
One-way ANOVA: †F = 36, p<0.001; Newman–Keuls post-hoc test: blepharospasm different from other groups, p<0.05. ‡F = 13.8, p<0.001; Newman–Keuls post-hoc test: blepharospasm different from other groups, p<0.05. §F = 6.12, p = 0.004; Newman–Keuls post-hoc test: blepharospasm different from other groups, p<0.05. ¶F = 4.79, p = 0.02; Newman–Keuls post-hoc test: blepharospasm different from other groups, p<0.05.