Table 2 Non-linear model fits for estimated age at diagnosis associations adjusted for motor scores
VariablenAdj R2p ValueNon-linear dfNon-linear p value
Striatal volume2610.20<0.000110.002
Speeded finger tapping rate (mean)4080.09<0.00013<0.01
Consistency in self-timed finger tapping4100.14<0.00013<0.01
Word list learning (HVLT)4250.05<0.000110.10
Odour identification4240.07<0.00011<0.01
  • Adj R2  =  variance accounted for by estimated years to diagnosis of Huntington’s disease (HD) after accounting for covariates (see statistical methods section) and degrees of freedom used for non-linear fit.

  • HVLT, Hopkins Verbal Learning Test; Non-linear df, degrees of freedom for non-linear fit; non-linear p value, p value for non-linear element of estimated years to HD diagnosis fit.