Table 2

EFNS/PNS electrodiagnostic criteria for chronic inflammatory demyelinating polyneuropathy (CIDP)1

I: “Definite CIDP”: at least one of the following:
    a. At least 50% prolongation of the motor distal latency above the upper limit of normal values in two nerves, or
    B. At least 30% reduction in motor conduction velocity below the lower limit of normal values in two nerves, or
    C. At least 20% prolongation of F-wave latency above the upper limit of normal values in two nerves (>50% if amplitude of negative peak compound muscle action potential (CMAP) <80% of lower limit of normal values), or
    D. Absence of F waves in two nerves if these nerves have amplitudes of distal negative peak at least 20% of lower limit of normal values+at least one other demyelinating parameter in at least one other nerve, or
    E. Partial motor conduction block: at least 50% amplitude reduction in the proximal negative peak CMAP relative to distal, if distal negative peak CMAP at least 20% of lower limit of normal values, in two nerves, or in one nerve+at least one other demyelinating parameter in at least one other nerve, or
    F. Abnormal temporal dispersion (>30% duration increase between proximal and distal negative peak CMAP) in at least two nerves, or
    G. Distal CMAP duration (interval between onset of the first negative peak and return to baseline of last negative peak) of at least 9 ms in at least one nerve nerve+at least one other demyelinating parameter in at least one other nerve
II. “Probable CIDP”
    At least 30% amplitude reduction in the proximal negative peak CMAP relative to distal, excluding the posterior tibial nerve, if distal negative peak CMAP at least 20% of lower limit of normal values in two nerves, or in one nerve nerve+at least one other demyelinating parameter in at least one other nerve
III. “Possible CIDP”
    As in “I” but in only one nerve
  • EFNS/PNS, European Federation of Neurological Societies/Peripheral Nerve Society.