Table 1

Demographic, clinical and MRI variables of subjects with and without post-stroke emotional lability

VariablePSEL (n = 74)No PSEL (n = 445)p Value
Age (years)*65.6 (9.9)65.6 (12.0)0.982¶
Female sex (n (%))38 (51.4)168 (37.8)0.027‡
Education (years)*4.2 (4.5)5.8 (4.8)0.008¶
MMSE score*24.8 (3.6)26.3 (3.1)<0.001†
NIHSS score*5.4 (3.8)4.3 (3.2)0.004†
Previous stroke (n (%))18 (24.3)82 (18.2)0.234‡
Presence of microbleeds (n (%))24 (32.4)100 (22.5)0.063‡
No of microbleeds1.7 (3.4)1.3 (5.0)0.031†
Localisation of microbleeds in (n (%))
    Frontal lobe9 (12.2)27 (6.1)0.056‡
    Temporal lobe8 (10.8)30 (6.7)0.213‡
    Parietal lobe8 (10.8)33 (7.4)0.316‡
    Occipital lobe2 (2.7)16 (3.6)1.000§
    Basal ganglia8 (10.8)39 (8.8)0.570‡
    Thalamus as whole12 (16.2)29 (6.5)0.004‡
        Anterior territory5 (6.9)9 (2.0)0.020‡
        Paramedian territory6 (8.1)14 (3.1)0.040‡
        Lateral territory6 (8.1)17 (3.8)0.097‡
        Posterior territory4 (5.4)10 (4.2)0.125§
    Brainstem8 (10.8)26 (5.8)0.110‡
    Cerebellum5 (6.8)31 (7.0)1.000§
  • *Values are mean (SD).

  • †Mann-Whitney U test; ‡χ2 test, §Fisher exact test; ¶t test.

  • MMSE, Mini-Mental State Examination; NIHSS, National Institute of Health Stroke Scale; PSEL, post-stroke emotional lability.