Table 1 Frequency of lesions in the five anatomical regions
LocationTissue sections examinedAreas of GM demyelinationAreas of WM demyelination
NoProportion that are pure GM lesions (%)*NoProportion that are pure WM lesions (%)
Cingulate132090977.8
Motor cortex12281002100
Deep GM133687.51361.5
Cerebellum137950.64156.1
Spinal cord374216.77014.3
  • Spinal cord values represent the pooled results from the three cord levels.

  • *Pure GM lesions (ie, lesions that are restricted to the GM and do not impinge on the adjacent WM).

  • GM, grey matter; WM, white matter.