Table 1 Clinical and demographic characteristics of clinically defined multiple sclerosis (MS) patients
Whole MS no = 65MS relapsing-remitting no = 35MS secondary progressive no = 20MS primary progressive no = 10
Age (years)41 (34 to 48)35 (29 to 41)45 (42 to 52)58 (46 to 60)
Sex: percentage male, male/female46%, 30/3546%, 16/1945%, 9/1150%, 5/5
EDSS2.5 (1 to 5)1.5 (0.5 to 2)5 (3.5 to 6.5)4.3 (3 to 6.5)
Disease duration (years)6 (3 to 13)4 (1 to 7)13 (6 to 21)10 (5 to 14)
HLA2 (DR15) haplotype carriers (C)+%+/tot54% 15/2871% 10/1427% 3/1167% 2/3
Cerebrospinal fluid oligoclonal bands+%+/tot91% 40/4486% 19/22100% 17/1780% 4/5
Compliance with at least three of four MRI revised McDonald criteria%+/tot100% 65/65100% 35/35100% 20/20100% 10/10
  • No significant differences were found among MS subgroups for age, expanded disability disease score (EDSS), or disease duration (ANOVA). HLA2 (DR15) genetic analysis was available in 28/65 patients, and cerebrospinal fluid in 44/65.