Table 1 Demographic and clinical characteristics of DM1 subjects with and without daytime sleepiness according to the Epworth Sleepiness Scale (ESS) and the multiple sleep latency test
CharacteristicsAll subjectsES⩾11ES<11MSL⩽8 minMSL>8 min
Age in years, mean (SD)49.7 (10.0)46.7 (10.1)52.7 (9.4)48.8 (6.9)50.3 (12.1)
BMI in kg/m2, mean (SD)28.7 (6.4)29.4 (8.3)(27.8) 3.828.3 (6.7)29.0 (6.3)
MIRS grade, mean (SD)3.3 (1.1)3.3 (1.0)3.3 (1.2)3.9 (0.7)*2.9 (1.2)
Depression T score, mean (SD)52.6 (9.2)53.9 (7.9)51.0 (10.6)52.5 (9.7)52.7 (9.0)
WAIS FSIQ, mean (SD)81.9 (8.8)82.8 (8.2)81.9 (8.9)80.9 (6.7)82.7 (10.2)
CTG repeats, mean (SD)868 (552)677 (494)*1010 (532)1000 (545)764 (546)
Habitual bedtime (h:min)23:44 (1:23)23:19 (1:09)*00:09 (1:29)23:56 (1:08)23:34 (1:32)
Habitual waketime (h:min)9:10 (1:30)9:19 (1:31)9:00 (1:30)9:25 (1:20)8:58 (1:36)
Habitual time in bed (h:min)9:26 (1:25)10:00 (1:17)**8:52 (1:20)9:29 (1:45)9:23 (1:10)
Cataplexy (%)23.343.0**5.032.017.0
Sleep paralysis (%)32.652.0**14.047.021.0
Hypnagogic hallucinations (%)23.333.014.026.021.0
  • *p<0.05; **p<0.01.

  • DM1, myotonic dystrophy type 1; ES, Epworth Sleepiness Scale scores; MIRS, muscular impairment rating scale; MSL, mean sleep latency; WAIS FSIQ, WAIS Full Scale IQ.