Table 1

Published individual outcome data on patients with primary forms of dystonia (and myoclonus dystonia) operated on with deep brain stimulation

PrimarySubtypeNo of individual patient dataAge at surgery, mean (SD)Duration of symptoms, mean (SD)Preop severity score, mean (SD)Percentage improvement in motor/severity score following deep brain stimulation, mean (SD), IQRReferences
GeneralisedDYT1 positive9122.6 (12.4)13.4 (11.7)53.8 (23.1)67.5 (27.7), 53.3–92.34–7 9 23 24 25 26 29 34 41 50–60
GeneralisedDYT1 negative10831.3 (16.2)15.4 (11.1)54.4 (23.6)55.8 (26.6), 38.6–79.34–7 9 24 28 29 33 41 50 51 55–63
GeneralisedUnknown1036.9 (16.1)17.0 (12.8)57.5 (22.7)51.9 (25.3), 20.8–71.46 10 23 26 64
FocalWriter's cramp646.6 (17.4)11.8 (9.3)3.3 (0.5)92 (12.9), 75–10065 66
FocalSpasmodic torticollis6750.0 (12.7)10.7 (7.4)24.9 (15.3)48.3 (41.2), 26–784 5 10 19 23 26 30 34 36 40 50 58 67–71
Focal/segmentalMeige1756.1 (9.1)8.5 (9.3)21.9 (11.0)64.3 (29.5), 55.5–82.223 38–40 45 46 72 73
Focal/segmentalMixed distribution3947.7 (15.6)12.6 (7.2)30.5 (16.1)57.1 (24.0), 38.5–79.34 13 14 25 26 53 58 60 74–77
Focal/segmentalAxial/camptocormia648.7 (15.1)12.4 (6.9)30.3 (16.1)66 (39.8), 33–87.578–81
Dystonia plusMyoclonus dystonia1033.9 (18.6)25.2 (19.4)44.2 (49.6)58 (19.2), 47.8–73.95 16 82–86