Table 2

Diagnostic ORs and 95% CI for predicting ICH versus ischaemic stroke in relation to potential clinical predictors in the OXVASC derivation cohort and the hospital clinic-based validation cohort

Derivation cohortValidation cohort
Infarct (n/%) n=317ICH (n/%) n=17Diagnostic OR (95% CI)p ValueInfarct (n/%) n=265ICH (n/%) n=15Diagnostic OR (95% CI)p Value
Demographic data
 Male184 (58)11 (65)1.3 (0.5 to 3.7)0.63158 (60)8 (53)0.6 (0.2 to 1.7)0.79
 Mean age (SD)74 (12)74 (11)0.8872 (11)73 (5)0.59
Symptoms
 Confusion25 (8)7 (41)8.2 (2.9 to 23)<0.00114 (5)6 (40)12.0 (3.7 to 38)<0.001
 Vomiting17 (5)8 (47)15.7 (5.4 to 46)<0.0016 (2)1 (7)3.1 (0.3 to 27)0.32
 Headache59 (19)9 (53)4.9 (1.8 to 13)0.00234 (13)3 (20)1.7 (0.5 to 6.3)0.43
Vascular risk factors
 Hyperlipidemia86 (27)5 (29)1.1 (0.4 to 3.3)0.7960 (23)4 (27)1.2 (0.4 to 4.0)0.75
 Previous MI38 (12)1 (6)0.5 (0.1 to 3.6)0.7047 (18)2 (13)0.7 (0.2 to 3.3)1.00
 Previous stroke46 (15)4 (24)1.8 (0.6 to 5.8)0.3028 (11)3 (20)2.1 (0.6 to 8.0)0.22
 Previous TIA56 (18)2 (12)0.6 (0.1 to 2.8)0.7523 (9)1 (7)0.8 (0.1 to 6.0)1.00
 Current smoker51 (16)3 (18)1.1 (0.3 to 4.0)0.7450 (19)1 (7)0.3 (0.0 to 2.4)0.32
 Hypertension198 (62)11 (65)1.1 (0.4 to 3.1)1.0162 (61)10 (67)1.3 (0.4 to 3.8)0.79
Premorbid medications
 Antiplatelet*141 (46)3 (23)0.3 (0.1 to 1.3)0.1595 (37)4 (36)1.0 (0.3 to 3.4)1.00
 Anticoagulation12 (4)4 (24)7.8 (2.2 to 28)0.0068 (3)4 (27)11.7 (3.0 to 45)0.002
Blood pressure at assessment
 <140/9081 (26)1 (6)1.0 (ref)151 (58)7 (47)1.0 (ref)
 140/90–159/99 mm Hg95 (30)2 (12)1.7 (0.2 to 19)1.0014 (5)0 (0)1.00
 160/100–179/109 mm Hg74 (23)2 (12)2.2 (0.2 to 25)0.6170 (26)3 (20)0.9 (0.2 to 3.7)1.00
 ≥180/110 mm Hg67 (21)12 (70)14.5 (1.8 to 114)0.00130 (11)5 (33)3.6 (1.1 to 12)0.04
  • * Excludes individuals on warfarin.