NMO patients | Control group | p Values | |
n=24 | n=12 | ||
Sex (women/men) | 17/7 | 8/4 | 0.95 |
Age in years (mean±SD) | 44.6±10.7 | 31.1±6.9 | 0.01 |
Disease duration, y (mean±SD) | 6.1±5.5 | — | |
No of relapses (mean±SD) | 4±2.3 | — | |
NMO-IgG antibody positive | 17/24 (58.6%) | — | |
NAWM | |||
NAA/creatinine (mean±SD) | 1.89±0.26 | 1.91±0.15 | 0.8 |
Choline/creatinine (mean±SD) | 1.03±0.18 | 1.08±0.14 | 0.7 |
NAGM | |||
NAA/creatinine (mean±SD) | 1.62±0.21 | 1.59±0.18 | 0.8 |
Choline/creatinine (mean±SD) | 0.89±0.2 | 0.94±0.2 | 0.7 |
Myo-inositol (mean±SD) | 0.42±0.12 | 0.42±0.18 | 0.9 |
NAA, N-acetyl aspartate; NAGM, normal-appearing grey matter; NAWM, normal-appearing white matter.