Table 2

Characteristics of the subgroup of patients with disease onset before the age of 30

N (%)Relapse onsetAge at onset of MSAge at first childNo of childrenEDSS 6 reachedTime to EDSS 6
n (%)Mean (SD; min to max)Mean (SD; min to max)Mean (range)n (%)Median (IQR)
(1) No children48 (32)47 (98)22.0 (4.6; 13 to 29)25 (52)8 (5.0 to 15.5)
(2) Children only before onset of MS32 (21)29 (91)26.9 (2.0; 21 to 29)22.9 (3.0; 18 to 29)1.6 (1 to 4)21 (66)16 (10.5 to 23.0)
(3) Children only after onset of MS58 (38)57 (98)21.7 (3.9; 9 to 28)27.6 (4.8; 19 to 43)1.6 (1 to 4)30 (52)21 (14.75 to 27.75)
(4) Children before and after onset of MS13 (9)12 (92)26.3 (2.1; 22 to 29)23.4 (3.3; 19 to 29)2.7 (2 to 5)6 (46)21.5 (14.25 to 29.0)